Trenbolone is an anabolic steroid that is used by bodybuilders for many years. Unfortunately, this preparation has never been claimed to be an appropriate medication for clinical needs. It is not approved for human use by the U. S. Food and Drug Administration (FDA). This drug has been demonized many times by media. Many articles have proclaimed that this preparation is very dangerous. But recent researches have displayed opposite facts. It is supposed that common attitude to trenbolone can be soon changed. Joshua Yarrow and his colleagues from the University of Florida claim that this preparation can be administrated as testosterone for hormone replacement therapy. The experts say that it is an appropriate alternative product to testosterone for the need mentioned above. Results of researches conducted by these experts have been published in the American Journal of Physiology – Endocrinology and Metabolism.
Moreover, the specialists proclaim that trenbolone enanthate has even some priorities over testosterone for some patients. Bodybuilders know and support the statements linked with this medicine. It is known that testosterone aromatases. As for trenbolone, it is turned neither to estradiol, nor to dihydrotestosterone (DHT). That’s why it doesn’t lead to adverse effects related to estrogen and DHT.
Joshua Yarrow reports about the researches conducted by him and his colleagues. Castrated rats have been given trenbolone enanthate. Even reduced doses of this preparation have induced their muscle size and kept bone mineral density. There have not been reported such negative effects, as enlargement of prostate or polycythemia in these lab rats.
But too enhanced doses of testosterone enanthate were required to cause the same anabolic effects in muscles as were produced by reduced dosages of trenbolone enanthate. But such unexpected reactions, as prostate enlargement and induced hemoglobin accompanied the enhanced measures of testosterone enanthate. It is suggested by the researchers that trenbolone acts like selective androgen receptor modulators, causing anabolic effects in muscles and bones without androgenic adverse consequences.
Professional competitive bodybuilders prefer taking trenbolone certain weeks before competitions because it causes fat loss. Furthermore, the studies have shown that the same dosages of trenbolone have stronger lipolytic effects than those of testosterone. It has been determined that more trenbolone an individual applies, the greater the fat loss is caused.
Since trenbolone lacks aromatization, it is commonly combined with such steroids, as testosterone, Dianabol or with another aromatizable steroid. The lack of aromatization leads trenbolone to disability to be used alone for testosterone replacement therapy. The non-aromatizable feature of this preparation is responsible for just partial protective effect of bones.
Nonetheless, it is possible to conclude that additional studies are required in order to use trenbolone for hormone replacement therapy.